Biologist, PhD, Clinical pathology specialist

Biology research manager, level A: "Cellular and molecular pathophysiology of degenerative and inflammatory rheumatic diseases" (resolution n.1, 02/01/2025)

1993: Degree in Biological Science, with honors, University of Bologna, Italy.

• 1999: PhD in Cellular biology and physiology, University of Bologna, Italy.
• 2003: Specialization in Clinical Pathology, with honors, University of Bologna, Italy.

• 1993-1998: attendance at the Experimental Pathology Department, University of Bologna.
• 1999-2001: research fellowship, Internal medicine and gastroenterology department, University of Bologna.
• 2001-2008: attendance at the Laboratory of Immunology and Genetics, IOR, Bologna, Italy (research temporary contract, fellowship).
• 1/2/2017-31/8/2018 Biology research manager, Laboratory of Medical Genetics, Medical Genetics Unit, Azienda Ospedaliero-Universitaria di Ferrara, Ferrara, Italy.
• 29/12/2008-31/10/2021: Biology research manager, Laboratory of Immunorheumatology and tissue regeneration, IOR, Bologna, Italy.
• 01/11/2021-present: Biology research manager, Medicine and Reumathology Unit, IOR, Bologna, Italy.

Fluent English and French.

Computer skills: office, Internet, software packages for graphical or statistical purposes, online databases for clinical research.

1998- Teacher of the “Molecular and interphase cytogenetic course”, European Leonardo da Vinci course for post-degree education.
Teaching contribution to ECM courses.
Tutor for degree thesis in Biological Sciences and Medical biotechnologies.

2001-2021- Paticipation in Oriented Fundamental Research Projects, University of Bologna.
2000- 2002- Participation in the Ministry of Health's project "Osteoporotic Fractures."
2000-2002- Participation in the Ministry of Health's project "Metallothioneins, zinc, and other molecules involved in inflammation as possible biological and genetic markers of immunosenescence and age-related inflammatory diseases."
2001-2002- Principal investigator Young Researchers Project (UniBo) "Mismatch repair and aging: study of microsatellite instability in the elderly."
2002-2005- Participation in the Ministry of Health project: "Influence of antioxidant nutritional factors, micronutrients, and macronutrients on the immune response to inflammation in the elderly."
2000-2003 Participation in the European Project ImAginE, “Immunology of Ageing in Europe”, UE FP5 (QLK6-CT-1999-02031).
2005-2007- Participation in the European Project “ZINCAGE- Nutritional zinc, oxidative stress and immunosenescence: biochemical, genetic and life style implication for healthy” UE FP6 (FOOD-CT-2003-506850).
2007-2008- Participation in the PRIN 2005 project: “Evaluation of chemokine production by osteoarthritis chondrocytes in culture”.
2008- Participation in the Fondazione Monte dei Paschi di Siena project: “Clinical translation of current preclinical knowledge in the field of musculoskeletal tissue engineering for biological reconstructions from traumatic and pathological substance losses”.
2010-2014 Participation in the European Project “ADIPOA- Adipose derived stromal cells for osteoarthritis treatment” (FP7 grant N. 241719).
2011-2015- Participation in the project MIUR FIRB RBAP10KCNS “Pathogenesis and molecular targets of degenerative diseases of the musculoskeletal system”.
2022-2023 Co-PI of the AO Spine Start-up Grant 22-032 “Local expression of epigenetic candidate biomarkers for Adolescent Idiopathic Scoliosis progression

Publications:
49 publications in journals with impact factor; 3 book chapters. H index=20.

Reviewer of the following scientific journasls:
Acta Biomaterialia, Acta Histochemica, Aging, Biomedicines, Biotechnology and Applied Biochemistry, Biotechnology journal, Cell biology and toxicology, Cell proliferation, Cell transplantation, Clinical and translational medicine, Drug design Development and Therapy, Experimental and Therapeutic Medicine, Genetics and molecular biology,  International Journal of Molecular Sciences, International Journal of Nanomedicine, Journal of Developmental Biology, Journal of Nanobiotechnology, Journal of Regenerative medicine, Journal of Translational Genetics and Genomics, Marine drugs, Mechanisms of Ageing and Development, Medical Science Monitor, Molecular Medicine Reports, Oncology reports, Orthopedic Research and Reviews, Osteoarthritis & cartilage, Oxidative medicine and cellular longevity, Polymers, Scientific Reports, Stem Cells and Development, Tissue Engineering.
 

Research fields: Medical Orthopedic Pathology and Regenerative Medicine. Cellular and molecular pathophysiology of degenerative and inflammatory rheumatic diseases. Cartilage pathophysiology: basic and clinical research. DNA damage during in vitro and in vivo cellular aging. Biosafety evaluation and monitoring during in vitro manipulation of cell therapy products. Study of mechanical stimulation effect in the maintenance of cartilage homeostasis.